Log In
Thursday 27th October 2016

DNA study insight into Alzheimer's

28th October 2013

The largest ever analysis of patients’ DNA is helping to create a clearer picture of what causes Alzheimer's disease.


The DNA of 17,000 patients and 37,000 healthy people was analysed in an attempt to understand more about the causes and development of the disease.

The results have increased the number of genes which are known to be linked to the dementia to 21.

By looking at these genes, and the functions they serve in the body, it has also helped researchers to look into the processes that contribute to the development of the disease. The analysis has indicated that the immune system may play a strong role in the development of the disease.

Prof Williams, the head of neurodegeneration at Cardiff University commented that: "We've doubled the number of genes discovered and a very strong pattern is emerging.

"There is something in the immune response which is causing Alzheimer's disease and we need to look at that."

The study also suggested the way the body deals with cholesterol and the way cells in the brain deal with big molecules in a process called endocytosis also seem to be involved.

Share this page


There are no comments for this article, be the first to comment!

Post your comment

Only registered users can comment. Fill in your e-mail address for quick registration.

Your email address:

Your comment will be checked by a Healthcare Today moderator before it is published on the site.

Article Information

Title: DNA study insight into Alzheimer's
Author: Martine Hamilton
Article Id: 24740
Date Added: 28th Oct 2013


BBC News

Recent Related Articles

Investigation into patient falls

External review into four maternal deaths

Alzheimer's drug study shows promise


Add to scrapbook
Show Comments
Add comment
Find all related articles


Mayden - Innovative cloud-based applications for healthcare
© Mayden Foundation 2016