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Help for menopause

17th March 2006

A study published in the Journal of Clinical Oncology shows that a single intramuscular injection of a depot preparation of medroxyprogesterone acetate (MPA) is more effective than antidepressants in reducing menopausal hot flushes.

Researchers compared a single 400-mg IM injection of depot MPA with a 6-week regimen of oral venlafaxine in 227 women experiencing disturbing hot flushes.

The team reported that hot flushes were reduced by 55% in the venlafaxine group, versus 79% in the MPA group.  A reduction in hot flushes by more than 50% from baseline was experienced by 46% of venlafaxine patients versus 74% of MPA patients.

Less nausea, less appetite loss, and less dizziness were also reported by the women in the MPA arm.

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