FAQ
Log In
Wednesday 29th March 2017
News
 › 
 › 

Higher antibiotic doses for obese

15th January 2010

Doctors have warned that rising rates of obesity may need to lead to a change in dose strength of antibiotics.

obese1

They say that as people get bigger the standard ‘one-size fits all’ dose may not clear infections in larger adults and increases the risk that resistance will develop.

An editorial in The Lancet, following research in Greece and America, says that GPs will need guidance on when to change doses according to a person’s size.

Size and the proportion of body fat can affect the concentration of antibiotics in the body, possibly reducing their effectiveness. However, while it may affect obese people there are also concerns that smaller people may be getting too much of a drug.

The Lancet says that dose adjustments could easily be made if research was done to guide doctors in treating obese patients.

Royal College of GPs chair Professor Steve Field said: “Patients are getting taller and larger and it does seem right that patients are given the appropriate strength of drug.

However, this might cost a lot of money because pharmaceutical companies would have to provide different doses of medication. At the moment, most come in two strengths and we would not want to see an increase in costs.”

Antibiotics expert Professor Hugh Pennington from the University of Aberdeen said it would be difficult to conduct effective studies on how size altered the effectiveness of such drugs.

The number of people classed as obese in England has risen from 15% in 1993 to 25% today.

 

Share this page

Comments

There are no comments for this article, be the first to comment!


Post your comment

Only registered users can comment. Fill in your e-mail address for quick registration.

Your email address:

Your comment will be checked by a Healthcare Today moderator before it is published on the site.

Article Information

Title: Higher antibiotic doses for obese
Author: Mark Nicholls
Article Id: 13780
Date Added: 15th Jan 2010

Sources

BBC News

Recent Related Articles

Brexit fears prompting EU nurses to desert the UK

Cap on new drugs

Children missing out on cancer drugs

UK needs to recruit 1.6m new care workers by 2022

Malaria drugs fail

Actions

Add to scrapbook
Show Comments
Add comment
Find all related articles

Tags

Mayden - Innovative cloud-based applications for healthcare
© Mayden Foundation 2017