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Hope for women with endometriosis

13th December 2010

Researchers have found two specific genome variants which raise the danger of endometriosis occurring in women.  

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Scientists from the University of Oxford, in addition to researchers from Australia and America, were part of the Nature Genetics study.

They examined the genomes of 5,500 women with endometriosis from the UK, Australia and America, and compared them against samples from 10,000 women who did not have the condition.

The researchers said their study provided indicators of why the condition occurred in some women.

They pinpointed two genes, chromosome 1 and chromosome 7, as vital indicators of whether a woman would develop endometriosis.

It is believed that chromosome 1 is near to a gene which is crucial for metabolising hormones and for female reproductive development.

Chromosome 7 is believed to have some involvement in the regulation of genes which help the womb and its lining to grow.

Dr Krina Zondervan, lead author of the study and research fellow at the University of Oxford, said: "Our study is a breakthrough because it provides the first strong evidence that variations in DNA make some women more likely to develop endometriosis."

"We now need to understand the effect of these variations on cells and molecules in the body," she added.

 

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Article Information

Title: Hope for women with endometriosis
Author: Jess Laurence
Article Id: 17004
Date Added: 13th Dec 2010

Sources

BBC News

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