FAQ
Log In
Saturday 3rd December 2016
News
 › 
 › 

'Male pill' stops sperm growth

31st October 2006

Scientists are developing a male contraceptive drug which stops the development process of sperm.

Tests on rats show blocking connections to cells which "nurture" developing sperm makes the animals infertile.

The US and Italian researchers say they used relatively low doses of the molecule and found no obvious side effects, and the effect was reversible.

When sperm are being made in the body in a process called spermatogenesis they sit next to other cells, called Sertoli cells, which nurse and help them grow.

If the connection between these two cell types is broken, infertility can result in men.

In the study authors used a recently developed molecule called Adjudin to dislodge the developing sperm from the Sertoli cells.

However Adjudin is also known to be toxic at high doses.

To get round this, the researchers linked it chemically to a hormone, called FSH, which acts in the testicles where sperm are made.

More research is needed to assess if the same approach could work in humans.


Share this page

Comments

There are no comments for this article, be the first to comment!


Post your comment

Only registered users can comment. Fill in your e-mail address for quick registration.

Your email address:

Your comment will be checked by a Healthcare Today moderator before it is published on the site.

Article Information

Title: 'Male pill' stops sperm growth
Author: Luisetta Mudie
Article Id: 1012
Date Added: 31st Oct 2006

Sources

BBC News

Recent Related Articles

Coil more effective than morning-after pill

New compound stops malaria

Actions

Add to scrapbook
Show Comments
Add comment
Find all related articles

Tags

M3 - For secure managed hosting over N3 or internet
© Mayden Foundation 2016