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Friday 28th October 2016

NICE guidance on treatment for neuropathic pain

25th March 2010

The National Institute for Health and Clinical Excellence (NICE) has published its first-ever guidance recommending which drugs GPs should prescribe adults with neuropathic pain, and in what order.

It says GPs should prescribe amitriptyline or pregabalin as a first line treatment, or oral duloxetine patients who have painful diabetic neuropathy. Patients who continue to suffer from neuropathic pain at the maximum tolerated dose of a first-line drug should be prescribed a drug from another therapeutic class – for example, amitriptyline if they have already been prescribed pregabalin, either in combination with the original drug.


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