Study of BCG vaccination10th April 2006
A study by Trunz, Fine and Dye, published in The Lancet, assesses and compares the cost and effect of BCG as an intervention against severe childhood tuberculosis in different regions of the world.
BCG vaccine has shown consistently high efficacy against childhood tuberculous meningitis and miliary tuberculosis, but variable efficacy against adult pulmonary tuberculosis and other mycobacterial diseases.
The study concludes that BCG vaccination should be retained in high-incidence countries as a strategy to supplement the chemotherapy of active tuberculosis as it is a highly cost-effective intervention against severe childhood tuberculosis.
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