Log In
Wednesday 23rd May 2018

Treatment hope from cough find

13th July 2009

A study by scientists at the University of Hull has identified a type of protein molecule which lives on nerve cells and causes a person to cough.


They are hopeful that the reseach could be used to treat chronic cough, which is suffered by around one in ten people in the UK.

Over 50% of new patients who go to see a GP are concerned about coughing.

Lead researcher Professor Alyn Morice said: "Chronic cough can be socially isolating and disabling...yet current treatment options are limited with remedies little better than honey and lemon."

Previous studies have examined how protein receptors on nerve cells transmit signals. One receptor known as TRPV1 produced a coughing reflex using the stimulus of chilli pepper extract.

Drugs were made which blocked the receptor, but tests showed that people who took the drugs could not feel heat properly and had raised body temperatures.

The researchers in Hull looked at a different receptor called TRPA1, which helps people feel the cold. 

It was found to produce a cough reflex when a stimulus of cinnamon extract was applied.

Professor Morice said: "When people have a cough they have a heightened sensitivity."

"However, we don't want to eliminate cough in patients because it is vital to keeping people well - it stops us getting pneumonia - so a return to normal sensitivity is the goal."

Share this page


There are no comments for this article, be the first to comment!

Post your comment

Only registered users can comment. Fill in your e-mail address for quick registration.

Your email address:

Your comment will be checked by a Healthcare Today moderator before it is published on the site.

Article Information

Title: Treatment hope from cough find
Author: Jess Laurence
Article Id: 12117
Date Added: 13th Jul 2009


BBC News

Recent Related Articles

Energy drinks ban in the UK


Add to scrapbook
Show Comments
Add comment
Find all related articles


Mayden - Innovative cloud-based web development for the healthcare sector
© Mayden Foundation 2018