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US withdraws migraine drugs

7th March 2007

The United States Food and Drug Administration (FDA) has ordered 15 unapproved migraine medications withdrawn from the market.

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The drugs have in common the active ingredient ergotamine, and are unrelated to the triptan class of drugs commonly used to treat migraine.

FDA-approved ergotamine drugs are unaffected.

The 15 brands are being withdrawn because they lack a crucial 'black box' safety warning telling patients not to use such drugs if they are also taking certain medications that block an enzyme needed to break down and remove ergotamine from the body.

 

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